Article
Association of extended interleukin-10 promoter haplotypes with disease susceptibility and manifestations in German patients with systemic lupus erythematosus.
Lupus - 1 Apr 2014
Schotte H, Willeke P, Becker H, Poggemeyer J, Gaubitz M, Schmidt H, Schlüter B
Abstract excerpt
OBJECTIVES: Associations of interleukin-10 (IL-10) promoter single nucleotide polymorphisms (SNPs) and their haplotypes with systemic lupus erythematosus (SLE) are unclear. We extended the analysis of established proximal IL-10 promoter haplotypes to a more distal SNP with functional capacity. METHODS: Two hundred and ten German caucasian SLE patients fulfilling the ACR criteria and 160 ethnically, age and sex...
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