Article
Relationship between duration of rheumatoid arthritis before knee joint surgery and HLA-DRB1 alleles: a retrospective study.
The Journal of rheumatology - 1 Dec 1997
Toda Y, Takemura S, Komuro H, Ono H, Tanabe T, Nakagawa T, Morimoto T, Ogawa R
Abstract excerpt
OBJECTIVE: To examine whether genetically determined factors can be used as predictors of requirement for knee joint surgery in the early phase of rheumatoid arthritis (RA). METHODS: We determined HLA-DRB1 alleles in 322 patients with seropositive RA by polymerase chain reaction and allele specif...
Topics
- Adult
- Age Factors
- Aged
- Aged, 80 and over
- Alleles
- Arthritis, Rheumatoid
- Female
- HLA-DR Antigens
- HLA-DRB1 Chains
- Humans
- Knee Joint
- Male
- Middle Aged
- Prognosis
- Retrospective Studies
- Time Factors
