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Article

MDL 201,307: a novel benzothiazepine modulator of multiple drug resistance.

Journal of experimental therapeutics & oncology - 1 Mar 1996

Newman R A, Fan D, Munson H R, Martin L A, Ahmed N K

Abstract excerpt

A series of novel benzothiazepine derivatives were evaluated for their relative potential to reverse multiple drug resistance (MDR) phenotype in vitro as well as for their relative cardiovascular activity and neurotoxicity. Compounds were evaluated for antiMDR activity using Chinese hamster ovary cells with derived resistance to either vincristine or doxorubicin, or a human lymphoblastic leukemia line with...

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PMID: 9414394

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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