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Article

A role for genomic instability in cellular radioresistance?

Cancer metastasis reviews - 1 Mar 1995

Morgan W F, Murnane J P

Abstract excerpt

Inherent cellular radioresistance plays a critical role in the failure of radiotherapy. Although the consequences of radioresistance are well known, the molecular, biological, and cellular bases of radioresistance remain a mystery. We propose that genomic instability, the increased rate of acquisition of alterations in the mammalian genome, can directly modulate cells' sensitivity to radiation. In particular,...

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Identifiers

PMID: 7606821
DOI: 10.1007/BF00690211

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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