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Article

Resistance to endotoxic shock in phospholipase A2 receptor-deficient mice.

The Journal of biological chemistry - 26 Dec 1997

Hanasaki K, Yokota Y, Ishizaki J, Itoh T, Arita H

Abstract excerpt

Mammals possess various types of secretory phospholipase A2, which differ in the primary structure and tissue distribution. The phosholipase A2 receptor (PLA2R) recognizes group IB phospholipase A2 (PLA2-IB) and mediates the PLA2-IB-induced biological responses in non-digestive organs, including eicosanoid production and contraction of airway smooth muscles. In this study, we generated PLA2R-deficient mice to...

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Identifiers

PMID: 9407054
DOI: 10.1074/jbc.272.52.32792

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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