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Article

Lysophosphatidic acid potentiates ACh receptor currents by G-protein-mediated activation of protein kinase C.

Brain research. Molecular brain research - 15 Oct 1997

Nishizaki T, Sumikawa K

Abstract excerpt

The effect of lysophosphatidic acid (lysoPA) on acetylcholine (ACh)-evoked currents was examined using normal and mutant Torpedo nicotinic ACh receptors expressed in Xenopus oocytes. LysoPA enhanced ACh-evoked currents in a washing time- and dose-dependent manner at concentrations of 0.1-3 microM, reaching a maximum of 210% 30 min after treatment, and instead, higher concentrations of lysoPA potentiated to a...

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Identifiers

PMID: 9406926
DOI: 10.1016/s0169-328x(97)00177-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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