Article
The Pumilio protein binds RNA through a conserved domain that defines a new class of RNA-binding proteins.
RNA (New York, N.Y.) - 1 Dec 1997
Zamore P D, Williamson J R, Lehmann R
Abstract excerpt
Translation of hunchback(mat) (hb[mat]) mRNA must be repressed in the posterior of the pre-blastoderm Drosophila embryo to permit formation of abdominal segments. This translational repression requires two copies of the Nanos Response Element (NRE), a 16-nt sequence in the hb[mat] 3' untranslated...
Topics
- Amino Acid Sequence
- Animals
- Conserved Sequence
- DNA-Binding Proteins
- Drosophila Proteins
- Drosophila melanogaster
- Humans
- Insect Proteins
- Molecular Sequence Data
- Mutation
- Protein Biosynthesis
- RNA, Messenger
- RNA-Binding Proteins
- Recombinant Fusion Proteins
- Sequence Homology, Amino Acid
- Species Specificity
- Transcription Factors