Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

No significant regulation of bicoid mRNA by Pumilio or Nanos in the early Drosophila embryo.

PloS one - 1 Jan 2018

Wharton Tammy H, Nomie Krystle J, Wharton Robin P

Abstract excerpt

Drosophila Pumilio (Pum) is a founding member of the conserved Puf domain class of RNA-binding translational regulators. Pum binds with high specificity, contacting eight nucleotides, one with each of the repeats in its RNA-binding domain. In general, Pum is thought to block translation in collaboration with Nanos (Nos), which exhibits no binding specificity in isolation but is recruited jointly to regulatory...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Drosophila melanogaster
Share to Drosophila Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Embryo, Nonmammalian

Share to Homeodomain Proteins

Share to RNA-Binding Proteins

Share to Testis

Share to Trans-Activators

Source

Open in PubMed Open full text

Identifiers

PMID: 29601592
DOI: 10.1371/journal.pone.0194865
PMCID: PMC5877865

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

No significant regulation of bicoid mRNA by Pumilio or Nanos in the early Drosophila embryo.PMID 29601592Read ↗

The Pumilio protein binds RNA through a conserved domain that defines a new class of RNA-binding proteins.Semantic proximity Read ↗

Binding of pumilio to maternal hunchback mRNA is required for posterior patterning in Drosophila embryos.Semantic proximity Read ↗

Sequential regulation of maternal mRNAs through a conserved cis-acting element in their 3’UTRsSemantic proximity Read ↗

Maternal Pumilio acts together with Nanos in germline development in Drosophila embryos.Semantic proximity Read ↗

Pumilio is essential for function but not for distribution of the Drosophila abdominal determinant Nanos.Semantic proximity Read ↗

A short 3’UTR motif regulates gene expression in bilateriansSemantic proximity Read ↗

A conserved abundant cytoplasmic long noncoding RNA modulates repression by Pumilio proteins in human cellsSemantic proximity Read ↗

The RNA binding domain of Pumilio antagonizes poly-adenosine binding protein and accelerates deadenylation.Semantic proximity Read ↗

The NHL domain of BRAT is an RNA-binding domain that directly contacts the hunchback mRNA for regulation.Semantic proximity Read ↗

The Bin3 RNA methyltransferase is required for repression of caudal translation in the Drosophila embryo.Semantic proximity Read ↗

Drosophila Brain Tumor is a translational repressor.Semantic proximity Read ↗

Loss of preimplantation embryo resulting from a Pum1 gene trap mutation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.