Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Long-term primary cultures of adult human hepatocytes.

Chemico-biological interactions - 6 Nov 1997

Ferrini J B, Pichard L, Domergue J, Maurel P

Abstract excerpt

In this work we have investigated a system of long-term primary cultures of adult human hepatocytes which, in contrast to those previously described, has the advantage of requiring neither the use of additive cells as in co-cultures, nor of matrix component preparations like Matrigel or collagen sandwich. This system has been used previously for long-term cultures of hepatocytes from young baboon, and some...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over
Share to Cells, Cultured

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cytochrome P-450 Enzyme System

Share to Gene Expression Regulation

Share to Isoenzymes

Share to Oxidation-Reduction

Source

Identifiers

PMID: 9402948
DOI: 10.1016/s0009-2797(97)00072-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Long-term primary cultures of adult human hepatocytes.PMID 9402948Read ↗

Cell-based models to study hepatic drug metabolism and enzyme induction in humansSemantic proximity Read ↗

Cell Lines: A Tool for In Vitro Drug Metabolism StudiesSemantic proximity Read ↗

Serum-Free, Long-Term Cultures of Human Hepatocytes: Maintenance of Cell Morphology, Transcription Factors, and Liver-Specific FunctionsSemantic proximity Read ↗

Application of spheroid culture to human hepatocytes and maintenance of their differentiationSemantic proximity Read ↗

Three-Dimensional Spheroid Primary Human Hepatocytes in Monoculture and Coculture with Nonparenchymal CellsSemantic proximity Read ↗

Expression and regulation of cytochrome P450 enzymes in primary cultures of human hepatocytesSemantic proximity Read ↗

Human hepatocyte systems for in vitro toxicology analysisSemantic proximity Read ↗

Hepatocyte cell lines: their use, scope and limitations in drug metabolism studiesSemantic proximity Read ↗

Human Hepatic Hepa<scp>RG</scp> Cells Maintain an Organotypic Phenotype with High Intrinsic <scp>CYP</scp>450 Activity/Metabolism and Significantly Outperform Standard HepG2/C3A Cells for Pharmaceutical and Therapeutic ApplicationsSemantic proximity Read ↗

Assessment of long-term functional maintenance of primary human hepatocytes to predict drug-induced hepatoxicity in vitroSemantic proximity Read ↗

Influence of culture time on the expression of drug‐metabolizing enzymes in primary human hepatocytes and hepatoma cell line HepG2Semantic proximity Read ↗

Recent Advances in Human Hepatocyte Culture SystemsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.