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Article

Cell-based models to study hepatic drug metabolism and enzyme induction in humans

1 Jun 2005

Abstract excerpt

Cell-based in vitro models are invaluable tools in elucidating the pharmacokinetic profile of a drug candidate during its drug discovery and development process. As biotransformation is one of the key determinants of a drug's disposition in the body, many in vitro models to study drug metabolism have been established, and others are still being developed and validated. This review is aimed at providing the reader...

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PMID: 16922654
DOI: 10.1517/17425255.1.1.75

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