Article
Differentially expressed genes in asbestos-induced tumorigenic human bronchial epithelial cells: implication for mechanism.
Carcinogenesis - 1 Nov 2000
Zhao Y L, Piao C Q, Wu L J, Suzuki M, Hei T K
Abstract excerpt
Although exposure to asbestos fibers is associated with the development of lung cancer, the underlying mechanism(s) remains unclear. Using human papillomavirus-immortalized human bronchial epithelial (BEP2D) cells, we previously showed that UICC chrysotiles can malignantly transform these cells in a stepwise fashion before they become tumorigenic in nude mice. In the present study we used cDNA expression arrays...
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