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Article

Possible cellular and molecular mechanisms for asbestos carcinogenicity.

American journal of industrial medicine - 1 Jan 1992

Walker C, Everitt J, Barrett J C

Abstract excerpt

Asbestos fibers may exert their carcinogenic effects on mesothelial cells and bronchial epithelial cells by direct and indirect mechanisms. Direct effects can occur following the physical interaction of fibers with target cells or by the generation of free radicals from the fiber surface; indirect effects, following the interaction of fibers with inflammatory cells can result in the production of cellular...

Topics

Animals
Asbestos
Carcinoma, Bronchogenic
Cell Transformation, Neoplastic
Chromosome Aberrations
Chromosome Disorders
Cricetinae
Growth Substances
Humans
Mesocricetus
Mesothelioma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Oxidants

Rats

Smoking

Source

Identifiers

PMID: 1536158
DOI: 10.1002/ajim.4700210214

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1536158-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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