Folding of barnase in the presence of the molecular chaperone SecB.

doi:10.1006/jmbi.1997.1398

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Article

Folding of barnase in the presence of the molecular chaperone SecB.

Journal of molecular biology - 28 Nov 1997

Stenberg G, Fersht A R

Abstract excerpt

SecB is a molecular chaperone dedicated to interact exclusively with proteins destined for translocation across membranes. We find that SecB interacts with barnase during its folding in a similar manner to its interaction with GroEL. On mixing acid-denatured barnase with SecB in a stopped-flow sp...

Topics

Bacillus
Bacterial Proteins
Escherichia coli
Kinetics
Molecular Chaperones
Mutation
Protein Binding
Protein Conformation
Protein Denaturation
Protein Folding
Ribonucleases
Spectrometry, Fluorescence

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