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Article

Folding of barnase in the presence of the molecular chaperone SecB.

Journal of molecular biology - 28 Nov 1997

Stenberg G, Fersht A R

Abstract excerpt

SecB is a molecular chaperone dedicated to interact exclusively with proteins destined for translocation across membranes. We find that SecB interacts with barnase during its folding in a similar manner to its interaction with GroEL. On mixing acid-denatured barnase with SecB in a stopped-flow spectrofluorimeter under conditions that favour refolding, we observe a series of fluorescence changes, corresponding to...

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Identifiers

PMID: 9398532
DOI: 10.1006/jmbi.1997.1398

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Folding of barnase in the presence of the molecular chaperone SecB.PMID 9398532Read ↗

Refolding of barnase in the presence of GroE.Semantic proximity Read ↗

Refolding of barnase mutants and pro-barnase in the presence and absence of GroEL.Semantic proximity Read ↗

The kinetic pathway of folding of barnase.Semantic proximity Read ↗

Transient folding intermediates characterized by protein engineering.Semantic proximity Read ↗

Interaction of SecB with intermediates along the folding pathway of maltose-binding protein.Semantic proximity Read ↗

Covalently dimerized SecA is functional in protein translocation.Semantic proximity Read ↗

Dynamics of the GroEL-protein complex: effects of nucleotides and folding mutants.Semantic proximity Read ↗

A calorimetric study of the thermal stability of barstar and its interaction with barnase.Semantic proximity Read ↗

Dynamic spin label study of the barstar-barnase complex.Semantic proximity Read ↗

Experimental assignment of the structure of the transition state for the association of barnase and barstar.Semantic proximity Read ↗

Simulation of the diffusional association of barnase and barstar.Semantic proximity Read ↗

The folding of an enzyme. III. Structure of the transition state for unfolding of barnase analysed by a protein engineering procedure.Semantic proximity Read ↗

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