Dynamics of the GroEL-protein complex: effects of nucleotides and folding mutants.

doi:10.1006/jmbi.1996.0235

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Article

Dynamics of the GroEL-protein complex: effects of nucleotides and folding mutants.

Journal of molecular biology - 26 Apr 1996

Sparrer H, Lilie H, Buchner J

Abstract excerpt

Chaperonins are a ubiquitous class of ring-shaped oligomeric protein complexes that are of crucial importance for protein folding in vivo. Analysis of the underlying functional principles had relied mainly on model proteins the (un)folding of which is dominated by irreversible side-reactions. We...

Topics

Adenine Nucleotides
Binding, Competitive
Carrier Proteins
Chaperonin 60
Escherichia coli Proteins
Kinetics
Maltose-Binding Proteins
Mutation
Periplasmic Binding Proteins
Protein Binding
Protein Folding
Protein Precursors

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