Article
Four dominant loci for the vascular responses by the antitumor polysaccharide, lentinan.
Immunogenetics - 1 Jan 1998
Maeda Y Y, Takahama S, Yonekawa H
Abstract excerpt
Lentinan, beta-1,6;1,3-glucan, showing an antitumor effect against mouse solid type tumors, can induce marked vascular dilation and hemorrhage (VDH) in very localized areas such as the ears, feet, and tails of mice in the early stages after its administration (Maeda et al. 1984). VDH has been found to be one of the T-cell-mediated responses triggered by lentinan. We reported previously that the responsiveness of...
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