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Article

Constitutive activity of a chimeric D2/D1 dopamine receptor.

Molecular pharmacology - 1 Dec 1997

Kozell L B, Neve K A

Abstract excerpt

Chimeric D1/D2 receptors were constructed to identify structural determinants of drug affinity and efficacy. We previously reported that chimeras that had D1 receptor transmembrane domain VII together with amino-terminal sequence from the D2 receptor were nonfunctional. D2/D1 chimeras were constructed that contained D2 receptor sequence at the amino- and carboxyl-terminal ends and D1 receptor sequence in the...

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PMID: 9396784
DOI: 10.1124/mol.52.6.1137

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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