Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The immune phenotype of AhR null mouse mutants: not a simple mirror of xenobiotic receptor over-activation.

Biochemical pharmacology - 15 Feb 2009

Esser Charlotte

Abstract excerpt

Intrinsic and induced cell differentiation and the cellular response to endogenous and exogenous signals are hallmarks of the immune system. Specific and common signalling cascades ensure a highly flexible and adapted response. Increasing evidence suggests that gene modulation by the aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor, is an important part of these processes. For decades the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune System
Share to Immune System Diseases
Share to Mice

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Knockout

Share to Phenotype

Share to Receptors, Aryl Hydrocarbon

Share to Signal Transduction

Share to Xenobiotics

Source

Identifiers

PMID: 18983984
DOI: 10.1016/j.bcp.2008.10.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The immune phenotype of AhR null mouse mutants: not a simple mirror of xenobiotic receptor over-activation.PMID 18983984Read ↗

Targeting AhR as a Novel Therapeutic Modality against Inflammatory Diseases.Semantic proximity Read ↗

Old Receptor, New Tricks—The Ever-Expanding Universe of Aryl Hydrocarbon Receptor Functions. Report from the 4th AHR Meeting, 29–31 August 2018 in Paris, FranceSemantic proximity Read ↗

Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development.Semantic proximity Read ↗

Role of Aryl Hydrocarbon Receptor Activation in Inflammatory Chronic Skin DiseasesSemantic proximity Read ↗

The aryl hydrocarbon receptor in the crossroad of signalling networks with therapeutic value.Semantic proximity Read ↗

Ahr null alleles: distinctive or different?Semantic proximity Read ↗

Human and rodent aryl hydrocarbon receptor (AHR): from mediator of dioxin toxicity to physiologic AHR functions and therapeutic options.Semantic proximity Read ↗

AhR Activation Leads to Attenuation of Murine Autoimmune Hepatitis: Single-Cell RNA-Seq Analysis Reveals Unique Immune Cell Phenotypes and Gene Expression Changes in the Liver.Semantic proximity Read ↗

Knockout of the aryl hydrocarbon receptor results in distinct hepatic and renal phenotypes in rats and mice.Semantic proximity Read ↗

The Aryl Hydrocarbon Receptor as an Immune-Modulator of Atmospheric Particulate Matter-Mediated AutoimmunitySemantic proximity Read ↗

Aryl hydrocarbon receptor-null allele mice have hematopoietic stem/progenitor cells with abnormal characteristics and functions.Semantic proximity Read ↗

Role of the xenobiotic receptor in inflammatory bowel disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.