Article
Association of platelet-activating factor acetylhydrolase gene polymorphism with premature coronary artery disease in Turkish patients.
Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology - 1 Jun 2006
Sekuri Cevad, Cam F Sirri, Tengiz Istemihan, Ercan Ertuğrul, Bayturan Ozgür, Berdeli Afig
Abstract excerpt
OBJECTIVE: Platelet-activating factor (PAF) is a phospholipid with multiple actions that is involved in inflammatory diseases as well as in atherogenesis. It is inactivated by a plasma enzyme, PAF-acetylhydrolase (PAF-AH). Deficiency of this enzyme in plasma is caused by a missense mutation in the gene (G994T). The aim of this study was to investigate association of this mutation with premature coronary artery...
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