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<i>Helicobacter pylori</i>infection and gastric carcinoma: Not all the strains and patients are alike

1 Jan 2016

Abstract excerpt

Gastric carcinoma (GC) develops in only 1%-3% of Helicobacter pylori (H. pylori) infected people. The role in GC formation of the bacterial genotypes, gene polymorphisms and host's factors may therefore be important. The risk of GC is enhanced when individuals are infected by strains expressing the oncoprotein CagA, in particular if CagA has a high number of repeats containing the EPIYA sequence in its...

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PMID: 26798436
DOI: 10.4251/wjgo.v8.i1.40

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