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Correlation between<i>cag</i>Pathogenicity Island Composition and<i>Helicobacter pylori-</i>Associated Gastroduodenal Disease

24 Oct 2003

Abstract excerpt

Helicobacter pylori infection is associated with a variety of outcomes ranging from seemingly asymptomatic coexistence to peptic ulcer disease and gastric cancer. The cag pathogenicity island (PAI) contains genes associated with a more aggressive phenotype and has been suggested to be a determinant of severe disease outcome. The cagA gene has served as a marker for the cag PAI. However, the presence of this...

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PMID: 14573679
DOI: 10.1128/iai.71.11.6573-6581.2003

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