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Article

MxA overexpression reveals a common genetic link in four Fanconi anemia complementation groups.

The Journal of clinical investigation - 1 Dec 1997

Li Y, Youssoufian H

Abstract excerpt

Fanconi anemia (FA) consists of a group of at least five autosomal recessive disorders that share both clinical (e.g., birth defects and hematopoietic failure) and cellular (e.g., sensitivity to cross-linking agents and predisposition to apoptosis) features with each other. However, a common pathogenetic link among these groups has not been established. To identify genetic pathways that are altered in FA and...

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Identifiers

PMID: 9389754
DOI: 10.1172/JCI119836
PMCID: PMC508494

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