Article
Functional correction of FA-C cells with FANCC suppresses the expression of interferon gamma-inducible genes.
Blood - 15 May 2001
Fagerlie S R, Diaz J, Christianson T A, McCartan K, Keeble W, Faulkner G R, Bagby G C
Abstract excerpt
Because hematopoietic cells derived from Fanconi anemia (FA) patients of the C-complementation group (FA-C) are hypersensitive to the inhibitory effects of interferon gamma (IFNgamma), the products of certain IFNgamma-inducible genes known to influence hematopoietic cell survival were quantified. High constitutive expression of the IFNgamma-inducible genes, IFN-stimulated gene factor 3 gamma subunit (ISGF3gamma),...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
