Article
Impaired DNA repair capacity in skin fibroblasts from various hereditary cancer-prone syndromes.
Mutation research - 1 Mar 1998
Abrahams P J, Houweling A, Cornelissen-Steijger P D, Jaspers N G, Darroudi F, Meijers C M, Mullenders L H, Filon R, Arwert F, Pinedo H M, Natarajan A P, Terleth C, Van Zeeland A A, van der Eb A J
Abstract excerpt
Host-cell reactivation (HCR) of UV-C-irradiated herpes simplex virus type 1 (HSV-1) has been determined in skin fibroblasts from the following hereditary cancer-prone syndromes: aniridia (AN), dysplastic nevus syndrome (DNS), Von Hippel-Lindau syndrome (VHL), Li-Fraumeni syndrome (LFS) and a fami...
Topics
- Aniridia
- Breast Neoplasms
- Cell Survival
- Cells, Cultured
- DNA Repair
- Dysplastic Nevus Syndrome
- Eukaryotic Cells
- Family Health
- Female
- Fibroblasts
- Genes, p53
- Herpesvirus 1, Human
- Humans
- Li-Fraumeni Syndrome