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Article

Impaired DNA repair capacity in skin fibroblasts from various hereditary cancer-prone syndromes.

Mutation research - 1 Mar 1998

Abrahams P J, Houweling A, Cornelissen-Steijger P D, Jaspers N G, Darroudi F, Meijers C M, Mullenders L H, Filon R, Arwert F, Pinedo H M, Natarajan A P, Terleth C, Van Zeeland A A, van der Eb A J

Abstract excerpt

Host-cell reactivation (HCR) of UV-C-irradiated herpes simplex virus type 1 (HSV-1) has been determined in skin fibroblasts from the following hereditary cancer-prone syndromes: aniridia (AN), dysplastic nevus syndrome (DNS), Von Hippel-Lindau syndrome (VHL), Li-Fraumeni syndrome (LFS) and a family with high incidence of breast and ovarian cancer. Cells from AN, DNS or VHL patients were found to exhibit...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9637247
DOI: 10.1016/s0921-8777(98)00009-3

Genes

VHL
ADA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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