Article
Mammalian α‐keto acid dehydrogenase complexes: gene regulation and genetic defects 1
1 Sept 1995
Abstract excerpt
Recent application of the tools of molecular biology has provided insight with respect to the structure, regulation, and defects of the genes encoding the PDC and the BCKADC. cDNAs for the alpha-KGDC have only recently been cloned. Evidence for long-term regulation of the expression of the subunits of the PDC and the BCKADC has been obtained. Detailed analyses of the promoter-regulatory regions of the genes...
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