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Iron-regulatory proteins: molecular biology and pathophysiological implications

1 Dec 2007

Abstract excerpt

Iron is required for key cellular functions, and there is a strong link between iron metabolism and important metabolic processes, such as cell growth, apoptosis and inflammation. Diseases that are directly or indirectly related to iron metabolism represent major health problems. Iron-regulatory proteins (IRPs) 1 and 2 are key controllers of vertebrate iron metabolism and post-transcriptionally regulate...

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PMID: 18053288
DOI: 10.1017/s1462399407000531

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