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Article

Biology of ferritin in mammals: an update on iron storage, oxidative damage and neurodegeneration.

Archives of toxicology - 1 Oct 2014

Finazzi Dario, Arosio Paolo

Abstract excerpt

Iron is an abundant transition metal that is essential for life, being associated with many enzyme and oxygen carrier proteins involved in a variety of fundamental cellular processes. At the same time, the metal is potentially toxic due to its capacity to engage in the catalytic production of noxious reactive oxygen species. The control of iron availability in the cells is largely dependent on ferritins,...

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PMID: 25119494
DOI: 10.1007/s00204-014-1329-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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