Article
Plant farnesyltransferase can restore yeast Ras signaling and mating.
Molecular and cellular biology - 1 Apr 1997
Yalovsky S, Trueblood C E, Callan K L, Narita J O, Jenkins S M, Rine J, Gruissem W
Abstract excerpt
Farnesyltransferase (FTase) is a heterodimeric enzyme that modifies a group of proteins, including Ras, in mammals and yeasts. Plant FTase alpha and beta subunits were cloned from tomato and expressed in the yeast Saccharomyces cerevisiae to assess their functional conservation in farnesylating Ras and a-factor proteins, which are important for cell growth and mating. The tomato FTase beta subunit (LeFTB) alone...
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