Analysis of exocytosis mutants indicates close coupling between regulated secretion and transcription activation in Tetrahymena.

doi:10.1073/pnas.94.20.10675

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Article

Analysis of exocytosis mutants indicates close coupling between regulated secretion and transcription activation in Tetrahymena.

Proceedings of the National Academy of Sciences of the United States of America - 30 Sept 1997

Haddad A, Turkewitz A P

Abstract excerpt

Stimulation of regulated secretory cells promotes protein release via the fusion of cytoplasmic storage vesicles with the plasma membrane. In Tetrahymena thermophila, brief exposure to secretagogue results in synchronous fusion of the entire set of docked dense-core granules with the plasma membr...

Topics

Animals
Calcium-Binding Proteins
Cytoplasmic Granules
Exocytosis
Genome, Protozoan
Green Fluorescent Proteins
Luminescent Proteins
Mutation
Promoter Regions, Genetic
Protozoan Proteins
RNA, Messenger
Tetrahymena thermophila
Transcriptional Activation

Source

Open in PubMed Open full text

Identifiers

PMID: 9380694
DOI: 10.1073/pnas.94.20.10675
PMCID: PMC23444

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9380694-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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