Article
Core formation and the acquisition of fusion competence are linked during secretory granule maturation in Tetrahymena.
Traffic (Copenhagen, Denmark) - 1 Apr 2005
Bowman Grant R, Elde Nels C, Morgan Garry, Winey Mark, Turkewitz Aaron P
Abstract excerpt
The formation of dense core secretory granules is a multistage process beginning in the trans Golgi network and continuing during a period of granule maturation. Direct interactions between proteins in the membrane and those in the forming dense core may be important for sorting during this process, as well as for organizing membrane proteins in mature granules. We have isolated two mutants in dense core granule...
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