Article
FcγRIIa cross-talk with TLRs, IL-1R, and IFNγR selectively modulates cytokine production in human myeloid cells.
Immunobiology - 1 Feb 2015
Vogelpoel Lisa T C, Hansen Ivo S, Visser Marijke W, Nagelkerke Sietse Q, Kuijpers Taco W, Kapsenberg Martien L, de Jong Esther C, den Dunnen Jeroen
Abstract excerpt
Myeloid antigen-presenting cells (APCs) tailor immune responses to the pathogen involved through the production of specific pro- and anti-inflammatory cytokines. It is becoming increasingly clear that the ultimate cytokine profile produced by myeloid APCs crucially depends on interaction between multiple pathogen recognizing receptors. In this respect, we recently identified an important role for cross-talk...
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