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Article

Regulation of Id3 cell cycle function by Cdk-2-dependent phosphorylation.

Molecular and cellular biology - 1 Dec 1997

Deed R W, Hara E, Atherton G T, Peters G, Norton J D

Abstract excerpt

The functions of basic helix-loop-helix (bHLH) transcription factors in activating differentiation-linked gene expression and in inducing G1 cell cycle arrest are negatively regulated by members of the Id family of HLH proteins. These bHLH antagonists are induced during a mitogenic signalling response, and they function by sequestering their bHLH targets in inactive heterodimers that are unable to bind to...

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Identifiers

PMID: 9372912
DOI: 10.1128/MCB.17.12.6815
PMCID: PMC232537

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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