Article
Rotavirus nonstructural glycoprotein NSP4 alters plasma membrane permeability in mammalian cells.
Journal of virology - 1 Dec 1997
Newton K, Meyer J C, Bellamy A R, Taylor J A
Abstract excerpt
The endoplasmic reticulum-localized transmembrane glycoprotein NSP4 of rotavirus is a key protein involved in rotavirus cytopathology. We have used a dual-recombinant vaccinia virus system to express NSP4 in monkey kidney epithelial cells at a level comparable to that observed during rotavirus in...
Topics
- Animals
- Cell Line
- Cell Membrane Permeability
- Gene Expression
- Genetic Vectors
- Glycoproteins
- Haplorhini
- Humans
- Mutation
- Recombinant Fusion Proteins
- Rotavirus
- Toxins, Biological
