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Article

Rotavirus genome segment 4 determines viral replication phenotype in cultured liver cells (HepG2).

Journal of virology - 1 Mar 1990

Ramig R F, Galle K L

Abstract excerpt

One-step growth determinations were performed with five strains of rotavirus in HepG2, a cell line derived from human liver. Three virus strains (SA11-C13, SA11-C14, and RRV) replicated in HepG2 cells and attained yields 10- to 100-fold above input titers. Two virus strains (B223 and SA11-4F) failed to replicate above input titer. Analysis of reassortants that segregated the genes of parental virus pairs able and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 2154590
DOI: 10.1128/JVI.64.3.1044-1049.1990
PMCID: PMC249215

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Source receipt: pubmed, retrieved 7 Sept 2026.

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