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Article

Genetic characterization of the rotavirus nonstructural protein, NSP4.

Virology - 29 Sept 1997

Kirkwood C D, Palombo E A

Abstract excerpt

The rotavirus nonstructural protein NSP4 plays a role in viral assembly by acting as an intracellular receptor for single-shelled particles and assisting in the translocation of these particles across the endoplasmic reticulum. Recently, NSP4 has been implicated in rotavirus virulence and is thought to act as an enterotoxin which triggers chloride secretion by a calcium-dependent signal transduction pathway....

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PMID: 9325233
DOI: 10.1006/viro.1997.8727

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