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Article

Genetic analysis of Murine hepatitis virus nsp4 in virus replication.

Journal of virology - 1 Nov 2007

Sparks Jennifer S, Lu Xiaotao, Denison Mark R

Abstract excerpt

Coronavirus replicase polyproteins are translated from the genomic positive-strand RNA and are proteolytically processed by three viral proteases to yield 16 mature nonstructural proteins (nsp1 to nsp16). nsp4 contains four predicted transmembrane-spanning regions (TM1, -2, -3, and -4), demonstrates characteristics of an integral membrane protein, and is thought to be essential for the formation and function of...

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Identifiers

PMID: 17855548
DOI: 10.1128/JVI.01257-07
PMCID: PMC2169011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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