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Article

Evolution to pathogenicity of the parvovirus minute virus of mice in immunodeficient mice involves genetic heterogeneity at the capsid domain that determines tropism.

Journal of virology - 1 Feb 2008

López-Bueno Alberto, Segovia José C, Bueren Juan A, O'Sullivan M Gerard, Wang Feng, Tattersall Peter, Almendral José M

Abstract excerpt

Very little is known about the role that evolutionary dynamics plays in diseases caused by mammalian DNA viruses. To address this issue in a natural host model, we compared the pathogenesis and genetics of the attenuated fibrotropic and the virulent lymphohematotropic strains of the parvovirus minute virus of mice (MVM), and of two invasive fibrotropic MVM (MVMp) variants carrying the I362S or K368R change in the...

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Source

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Identifiers

PMID: 18045943
DOI: 10.1128/JVI.01692-07
PMCID: PMC2224436

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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