Article
Rapid fixation of deleterious alleles can be caused by Muller's ratchet.
Genetical research - 1 Aug 1997
Charlesworth B, Charlesworth D
Abstract excerpt
Theoretical arguments are presented which suggest that each advance of Muller's ratchet in a haploid asexual population causes the fixation of a deleterious mutation at a single locus. A similar process operates in a diploid, fully asexual population under a wide range of parameter values, with respect to fixation within one of the two haploid genomes. Fixations of deleterious mutations in asexual species can...
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