Effects of deleterious mutations on the fixation of chromosomal inversions on autosomes and sex chromosomes.

Abstract excerpt

Deleterious mutations have multiple effects on the fate of chromosomal inversions. In this article, we use individual-based simulations to estimate the fixation probabilities of neutral inversions under a constant input of deleterious mutations. As shown previously, we find that "lucky" inversions carrying a lower-than-average mutation load are initially favored and tend to selectively spread. Our results also...

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