Article
The solitary wave of asexual evolution.
Proceedings of the National Academy of Sciences of the United States of America - 21 Jan 2003
Rouzine Igor M, Wakeley John, Coffin John M
Abstract excerpt
Using a previously undescribed approach, we develop an analytic model that predicts whether an asexual population accumulates advantageous or deleterious mutations over time and the rate at which either process occurs. The model considers a large number of linked identical loci, or nucleotide sites; assumes that the selection coefficient per site is much less than the mutation rate per genome; and includes back...
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