Article
A valine421 to methionine mutation in IS6 of the hscp voltage-gated sodium channel associated with pyrethroid resistance in Heliothis virescens F.
Biochemical and biophysical research communications - 29 Oct 1997
Park Y, Taylor M F, Feyereisen R
Abstract excerpt
Multiple mutations in a locus encoding a voltage-gated sodium channel have been predicted for pyrethroid resistance in insects. Previously we reported a mutation associated with pyrethroid resistance, Leu1029 to His, in domain II transmembrane segment S6 (IIS6) of the Heliothis virescens F. sodium channel (para homologue) hscp locus. Sequence analysis of additional resistance haplotypes 5' to this mutation in the...
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