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Functional characterization of voltage-gated sodium channels in two mirid pests and identification of kdr mutations in pyrethroid resistant Lygus lineolarispopulation.

Insect biochemistry and molecular biology - 1 Mar 2026

Du Yuzhe, Scheibener Shane, Zhu Yu-Cheng, Perera Omaththage P, Reddy Gadi V P, Zhorov Boris S

Abstract excerpt

Lygus lineolaris and Lygus hesperus are economically important pests that cause substantial damage to wide variety of crops in the United States. In this study, we isolated 17 full-length voltage-gated sodium channels cDNA clones encoding 14 unique splicing variants from a susceptible strain of L. hesperus (sLhNav), two variants from a susceptible L. lineolaris strain (sLlNav), and 8 clones encoding 7 variants...

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PMID: 41500431
DOI: 10.1016/j.ibmb.2026.104486

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