Article
Mutations in the Bemisia tabaci para sodium channel gene associated with resistance to a pyrethroid plus organophosphate mixture.
Insect biochemistry and molecular biology - 1 Dec 2002
Morin S, Williamson M S, Goodson S J, Brown J K, Tabashnik B E, Dennehy T J
Abstract excerpt
The voltage-gated sodium channel is the primary target site of pyrethroid insecticides. In some insects, super knockdown resistance (super-kdr) to pyrethroids is caused by point mutations in the linker fragment between transmembrane segments 4 and 5 of the para-type sodium channel protein domain II (IIS4-5). Here, we identify two mutations in the IIS4-5 linker of the para-type sodium channel of the whitefly,...
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