Article
The combination of epidermal growth factor and transforming growth factor-beta induces novel phenotypic changes in mouse liver stem cell lines.
Journal of cell science - 1 Dec 1997
Isfort R J, Cody D B, Stuard S B, Randall C J, Miller C, Ridder G M, Doersen C J, Richards W G, Yoder B K, Wilkinson J E, Woychik R P
Abstract excerpt
Mouse liver stem cell (oval cell) lines were investigated in order to determine the role which two families of growth and differentiation factors (GDFs), epidermal growth factor (EGF) family and transforming growth factor beta (TGF-beta) family, play in liver regeneration. EGF family members, including EGF, amphiregulin, betacellulin, heparin-binding epidermal growth factor, and TGF-alpha, were mitogenic for oval...
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