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Article

Receptor phenotype underlies differential response of hepatocytes and nonparenchymal cells to heparin-binding fibroblast growth factor type 1 (aFGF) and type 2 (bFGF).

In vitro cellular & developmental biology : journal of the Tissue Culture Association - 1 Jan 2000

Kan M, Yan G C, Xu J, Nakahara M, Hou J

Abstract excerpt

Heparin-binding fibroblast growth factors (HBGF) have been implicated in the regeneration of both parenchymal and nonparenchymal cells of the liver. The response to and phenotype of hepatocyte receptors for HBGF-1 (acidic fibroblast growth factor) and HBGF-2 (basic fibroblast growth factor) were compared to keratinocytes, fibroblasts, and endothelial cells. HBGF-1 stimulated DNA synthesis in hepatocytes,...

Topics

Animals
Binding, Competitive
Cells, Cultured
Endothelium
Fibroblast Growth Factor 1
Fibroblast Growth Factor 2
Fibroblasts
Gene Expression Regulation
Keratinocytes
Liver

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Liver Regeneration

Phenotype

Rats

Receptors, Cell Surface

Receptors, Fibroblast Growth Factor

Source

Identifiers

PMID: 1381709
DOI: 10.1007/BF02634135

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1381709-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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