Article
Inhibition of CD4 translation mediated by human immunodeficiency virus type 1 envelope protein in a cell-free system.
The Journal of biological chemistry - 14 Nov 1997
Bour S, Geleziunas R, Wainberg M A
Abstract excerpt
The human immunodeficiency virus type 1 (HIV-1) employs a number of complex strategies to interfere with the synthesis, stability, and subcellular localization of its specific cellular receptor CD4. To define better the mechanisms of inhibition of CD4 expression, we used a rabbit reticulocyte lys...
Topics
- Animals
- Binding Sites
- CD4 Antigens
- Cell-Free System
- Genes, Viral
- HIV Envelope Protein gp160
- Human Immunodeficiency Virus Proteins
- Humans
- Mutation
- Protein Biosynthesis
- RNA, Messenger
- Rabbits
- Viral Regulatory and Accessory Proteins