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Article

Inhibition of CD4 translation mediated by human immunodeficiency virus type 1 envelope protein in a cell-free system.

The Journal of biological chemistry - 14 Nov 1997

Bour S, Geleziunas R, Wainberg M A

Abstract excerpt

The human immunodeficiency virus type 1 (HIV-1) employs a number of complex strategies to interfere with the synthesis, stability, and subcellular localization of its specific cellular receptor CD4. To define better the mechanisms of inhibition of CD4 expression, we used a rabbit reticulocyte lysate in vitro system, in which cDNAs derived from HIV-1-infected cells were used to generate mRNA for the Tat, Vpu, and...

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Identifiers

PMID: 9360974
DOI: 10.1074/jbc.272.46.29005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Inhibition of CD4 translation mediated by human immunodeficiency virus type 1 envelope protein in a cell-free system.PMID 9360974Read ↗

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Elements distinct from human immunodeficiency virus type 1 splice sites are responsible for the Rev dependence of env mRNASemantic proximity Read ↗

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