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Article

Binding of the eukaryotic translation elongation factor 1A with the 5'UTR of HIV-1 genomic RNA is important for reverse transcription.

Virology journal - 6 Aug 2015

Li Dongsheng, Wei Ting, Jin Hongping, Rose Amanda, Wang Rui, Lin Min-Hsuan, Spann Kirsten, Harrich David

Abstract excerpt

BACKGROUND: The cellular protein eukaryotic translation elongation factor 1A (eEF1A) binds to aminoacylated transfer RNAs and delivers them to the ribosome during translation. eEF1A also binds to RNA secondary structures present in genomes of several RNA viruses and plays important roles in their replication. As a RNA binding protein, whether eEF1A can bind with HIV-1 genomic RNA has not been investigated and was...

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Share to 5' Untranslated Regions
Share to Genome, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Inverted Repeat Sequences

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Share to Peptide Elongation Factor 1

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Source

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Identifiers

PMID: 26242867
DOI: 10.1186/s12985-015-0337-x
PMCID: PMC4525723

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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