Article
Biochemistry of Alzheimer's disease amyloid plaques.
Clinical biochemistry - 1 Oct 1993
Fraser P E, Lévesque L, McLachlan D R
Abstract excerpt
One of the principal identifying features of Alzheimer's disease (AD) is the extracellular deposition of fibrous protein aggregates in the form of amyloid plaques. The major component of these deposits is the amyloid beta (A beta) protein that is a proteolytic fragment of the integral membrane am...
Topics
- Alzheimer Disease
- Amino Acid Sequence
- Amyloid beta-Peptides
- Amyloid beta-Protein Precursor
- Animals
- Cell Death
- Humans
- Mice
- Mice, Transgenic
- Molecular Sequence Data
- Mutation
- Neurons