Article
A uniform genomic minor histocompatibility antigen typing methodology and database designed to facilitate clinical applications.
PloS one - 20 Dec 2006
Spierings Eric, Drabbels Jos, Hendriks Matthijs, Pool Jos, Spruyt-Gerritse Marijke, Claas Frans, Goulmy Els
Abstract excerpt
BACKGROUND: Minor Histocompatibility (H) antigen mismatches significantly influence the outcome of HLA-matched allogeneic stem cell transplantation. The molecular identification of human H antigens is increasing rapidly. In parallel, clinical application of minor H antigen typing has gained interest. So far, relevant and simple tools to analyze the minor H antigens in a quick and reliable way are lacking....
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