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Article

Study of the role of the htrB gene in Salmonella typhimurium virulence.

Infection and immunity - 1 Nov 1997

Jones B D, Nichols W A, Gibson B W, Sunshine M G, Apicella M A

Abstract excerpt

We have undertaken a study to investigate the contribution of the htrB gene to the virulence of pathogenic Salmonella typhimurium. An htrB::mini-Tn10 mutation from Escherichia coli was transferred by transduction to the mouse-virulent strain S. typhimurium SL1344 to create an htrB mutant. The S. typhimurium htrB mutant was inoculated into mice and found to be severely limited in its ability to colonize organs of...

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Identifiers

PMID: 9353064
DOI: 10.1128/iai.65.11.4778-4783.1997
PMCID: PMC175685

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