Article
A 59 kiloDalton outer membrane protein of Salmonella typhimurium protects against oxidative intraleukocytic killing due to human neutrophils.
Molecular microbiology - 1 Feb 1990
Stinavage P S, Martin L E, Spitznagel J K
Abstract excerpt
We have isolated a Salmonella typhimurium (ST) mutant, JKS400, deficient in the production of a surface-exposed outer membrane protein (Omp) and phenotypically hypersensitive to the oxidative antimicrobial mechanism of polymorphonuclear leukocytes (PMNs). This Omp migrated at approximately 59 kiloDaltons (kD) in sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE). We found with P22 transduction...
Topics
- Acid Phosphatase
- Bacterial Outer Membrane Proteins
- Chromosome Mapping
- Drug Resistance, Microbial
- Hydrogen Peroxide
- Lipopolysaccharides
- Molecular Weight
- Mutation
- Neutrophils
- Oxidation-Reduction